Basic Information

Symbol
RHEB
RNA class
mRNA
Alias
Ras Homolog, MTORC1 Binding RHEB2 Ras Homolog Enriched In Brain 2 Ras Homolog Enriched In Brain GTP-Binding Protein Rheb EC 3.6.5.-
Location (GRCh38)
7:151466012-151520120
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_005614.4
Sequence length
2046.0 nt
GC content
0.4800

Transcripts

ID Sequence Length GC content
NM_005614.4 NCBI
GGGAGGGUCAUGACGCAGCGAGUUUCAGUCGUGACUUUUCUGGGGGCAU… 2046 nt 0.4800
Summary

This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008] CIViC Summary for RHEB Gene

Forensic Context

No relevant information is available at the moment.