Basic Information

Symbol
RHOXF2B
RNA class
mRNA
Alias
Rhox Homeobox Family Member 2B Rhox Homeobox Family, Member 2B
Location (GRCh38)
X:120072264-120077690
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl UniProt GTEx

MANE select

Transcript ID
NM_001099685.3
Sequence length
1257.0 nt
GC content
0.5219

Transcripts

ID Sequence Length GC content
NM_001099685.3 NCBI
GGAUACACUGUUGCUGAGUCUAGACACCAGAAGAACGUUGCAGGCGGCG… 1257 nt 0.5219
Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in positive regulation of gene expression. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans identified the RHOXF2B as a differentially expressed mRNA that was downregulated in heart failure compared to myocardial fibrosis in blood samples from patients, as determined by RNA sequencing [Wang et al. DOI:10.3389/fcvm.2021.664044].