Basic Information

Symbol
RIDA
RNA class
mRNA
Alias
Reactive Intermediate Imine Deaminase A P14.5 Reactive Intermediate Imine Deaminase A Homolog 2-Iminobutanoate/2-Iminopropanoate Deaminase Heat-Responsive Protein 12 HRSP12 UK114 PSP 14.5 KDa Translational Inhibitor Protein Translation Inhibitor L-PSP Ribonuclease Translational Inhibitor P14.5 UK114 Antigen Homolog Hp14.5 Reactive Intermediate/Imine Deaminase A Homolog Translational Inhibitor Protein P14.5 Perchloric Acid-Soluble Protein Ribonuclease UK114 EC 3.5.99.10
Location (GRCh38)
8:98102336-98117175
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_005836.3
Sequence length
987.0 nt
GC content
0.3840

Transcripts

ID Sequence Length GC content
NM_005836.3 NCBI
AGUCCAGUAAGAAGCCAGCAGGGCUGGUGCUGGGGCUUCUUCUCCUGAA… 987 nt 0.3840
Summary

Enables mRNA binding activity. Involved in mRNA catabolic process and mRNA destabilization. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that dietary methylmercury exposure significantly altered hippocampal protein and RNA expression, with the RIDA being upregulated at both the protein and RNA levels in response to a high dose, indicating its role in antioxidant activity and the handling of toxic metabolites [Mellingen et al. DOI:10.1093/Mtomcs/Mfab022]. A study in mouse primary cortical astrocytes demonstrated that brief ethanol exposure significantly activated the RIDA as part of a broader transcriptional response to stress [Pignataro et al. DOI:10.1002/Brb3.125].