Basic Information

Symbol
RILPL2
RNA class
mRNA
Alias
Rab Interacting Lysosomal Protein Like 2 Rab-Interacting Lysosomal Protein-Like 2 P40phox-Binding Protein RILP-Like Protein 2 FLJ30380 FLJ32372 MGC7036 RLP2 Rab Interacting Lysosomal Protein-Like 2
Location (GRCh38)
12:123409714-123436684
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_145058.3
Sequence length
1752.0 nt
GC content
0.5320

Transcripts

ID Sequence Length GC content
NM_145058.3 NCBI
CUUUUCCGUUGUCCCUUCGCGCCCCAAACCACAUCCUGGAGCGCACUCU… 1752 nt 0.5320
Summary

This gene encodes a protein that contains a rab-interacting lysosomal protein-like domain. This protein may be involved in regulating lysosome morphology. This protein may also be a target for the Hepatitis C virus and assist in viral replication. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Forensic Context

A study in mice demonstrated that acute alcohol exposure during neurulation induces rapid transcriptomic changes in the rostroventral neural tube, with RILPL2, a gene involved in cilia biogenesis, being significantly up-regulated (+0.44 Log2FC) 2 hours post-exposure [Boschen et al. DOI:10.1016/J.Alcohol.2022.09.001].