Basic Information

Symbol
RND1
RNA class
mRNA
Alias
Rho Family GTPase 1 Rho6 ARHS RHOS Rho-Related GTP-Binding Protein Rho6 Ras Homolog Gene Family, Member S RHO6 Rnd1
Location (GRCh38)
12:48857145-48865870
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_014470.4
Sequence length
1653.0 nt
GC content
0.5469

Transcripts

ID Sequence Length GC content
NM_014470.4 NCBI
AGUUGGAGGGAGGCAGGGAAUCUGGCUUGAUUGGCGUGCUGAGACGCAC… 1653 nt 0.5469
Summary

This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014]

Forensic Context

A study in human and rat skin demonstrated that ultraviolet-B irradiation induces significant transcriptional changes, with the RND1 being up-regulated in both species, showing a fold change of 26.5 in human and 10.0 in rat skin [Dawes et al. DOI:10.1371/journal.pone.0093338].