Basic Information

Symbol
RPS6KA5
RNA class
mRNA
Alias
Ribosomal Protein S6 Kinase A5 MSK1 RLPK Nuclear Mitogen- And Stress-Activated Protein Kinase 1 90 KDa Ribosomal Protein S6 Kinase 5 Ribosomal Protein S6 Kinase Alpha-5 RSK-Like Protein Kinase S6K-Alpha-5 EC 2.7.11.1 RSKL Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 Ribosomal Protein S6 Kinase, 90kD, Polypeptide 5 EC 2.7.11 MSPK1
Location (GRCh38)
14:90847861-91060682
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_004755.4
Sequence length
26829.0 nt
GC content
0.3836

Transcripts

ID Sequence Length GC content
NM_001322237.2 NCBI
AGCCCGGGAAUGAGCGGCGGGCACCAGGCAUCGGGGCCAGCGCAGCCGC… 26626 nt 0.3813
NM_001322238.2 NCBI
AGCCCGGGAAUGAGCGGCGGGCACCAGGCAUCGGGGCCAGCGCAGCCGC… 26335 nt 0.3811
NM_004755.4 NCBI
GCGGUACUAGCGGUGCCCGCCGAAGGGGGAGGAGGCGAGGAGCGAGCCG… 26829 nt 0.3836
NM_182398.3 NCBI
GCGGUACUAGCGGUGCCCGCCGAAGGGGGAGGAGGCGAGGAGCGAGCCG… 2298 nt 0.4252
Showing 11 to 14 of 14 entries
Summary

Enables ATP binding activity and protein kinase activity. Involved in several processes, including interleukin-1-mediated signaling pathway; protein modification process; and regulation of DNA-templated transcription. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Forensic Context

A study in humans using RNA-sequencing of serum identified RPS6KA5 as an upregulated mRNA in sepsis patients compared to healthy controls, with a fold change of 11.60, classifying it as a potential biomarker [Yu et al. DOI:10.1016/j.heliyon.2023.e15034].