Ras Related GTP Binding C
GTR2
Ras-Related GTP-Binding Protein C
GTPase-Interacting Protein 2
FLJ13311
TIB929
Ras-Related GTP Binding C
Rag C Protein
EC 3.6.5.-
LNGODS
LNGOS
Rag C
RAGC
RagC
This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Forensic Context
A study in mice demonstrated that chronic methamphetamine administration significantly dysregulated the RRAGC in microglia, where it is involved in the autophagy pathway [Oladapo et al. DOI:10.3390/Ijms26020649].