Basic Information

Symbol
RUNDC3A
RNA class
mRNA
Alias
RUN Domain Containing 3A RAP2IP RPIP8 RUN Domain-Containing Protein 3A Rap2-Interacting Protein 8 RPIP-8 RaP2 Interacting Protein 8
Location (GRCh38)
17:44307947-44318675
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden death from CNS diseases
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001144825.2
Sequence length
2005.0 nt
GC content
0.6289

Transcripts

ID Sequence Length GC content
NM_001144825.2 NCBI
GCCCCGGCUCAGCACCUCGGAGAGCUCCCUCCCCGGCCUUGUUUUGCUC… 2005 nt 0.6289
NM_001144826.2 NCBI
GCCCCGGCUCAGCACCUCGGAGAGCUCCCUCCCCGGCCUUGUUUUGCUC… 1792 nt 0.6004
NM_006695.5 NCBI
GCCCCGGCUCAGCACCUCGGAGAGCUCCCUCCCCGGCCUUGUUUUGCUC… 1807 nt 0.6015
Summary

Predicted to enable GTPase regulator activity. Predicted to be involved in positive regulation of cGMP-mediated signaling. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2025]

Forensic Context

A study in mice demonstrated that RAP2 interacting protein 8 (RPIP8) gene expression was significantly enhanced in brain tissue from animals subjected to 25 minutes of neck ligation-induced hypoxia and dissected 30 minutes post-mortem (Group A25-30) compared to controls, as confirmed by comparative RT-PCR and statistical analysis (ANOVA with Bonferroni/Dann post hoc test) [Ikematsu et al. DOI:10.1016/J.Forsciint.2006.08.015].