Basic Information

Symbol
RXRG
RNA class
mRNA
Alias
Retinoid X Receptor Gamma NR2B3 Nuclear Receptor Subfamily 2 Group B Member 3 RXR-Gamma RXRgamma Retinoic Acid Receptor RXR-Gamma Retinoid X Receptor, Gamma RXRC
Location (GRCh38)
1:165400922-165445355
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_006917.5
Sequence length
1966.0 nt
GC content
0.5254

Transcripts

ID Sequence Length GC content
NM_001256570.2 NCBI
ACCAGCUGCUGCCGCCACAGCCGUCUCAAACGCACUAUGUGGACUCUCC… 2024 nt 0.5247
NM_001256571.2 NCBI
AGCAGCCUGAGACCCUGAGCAGUGUUCUGGGCUUGGGCUCCGGAACCAC… 1670 nt 0.5102
NM_006917.5 NCBI
ACCAGCUGCUGCCGCCACAGCCGUCUCAAACGCACUAUGUGGACUCUCC… 1966 nt 0.5254
Summary

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]

Forensic Context

No relevant information is available at the moment.