Basic Information

Symbol
S100A14
RNA class
mRNA
Alias
S100 Calcium Binding Protein A14 S100A15 BCMP84 Protein S100-A14 S114 Breast Cancer Membrane Protein 84 S100 Calcium-Binding Protein A14
Location (GRCh38)
1:153614255-153616996
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_020672.3
Sequence length
1054.0 nt
GC content
0.5332

Transcripts

ID Sequence Length GC content
NM_020672.3 NCBI
CCUCCUGUCUUGUCUCAGCGGCUGCCAACAGAUCAUGAGCCAUCAGCUC… 1054 nt 0.5332
Summary

This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011]

Forensic Context

A study in mice demonstrated that S100A14 was used as a protein marker in multiplex immunofluorescence to identify cells within the molecular profiling of radiation-induced skin injury [Yu et al. DOI:10.1186/s40164-025-00596-w].