Basic Information

Symbol
SALL1
RNA class
mRNA
Alias
Spalt Like Transcription Factor 1 ZNF794 Hsal1 Zinc Finger Protein Spalt-1 Zinc Finger Protein SALL1 Zinc Finger Protein 794 Sal-Like Protein 1 Sal-1 TBS Epididymis Secretory Protein Li 89 Spalt-Like Transcription Factor 1 Sal (Drosophila)-Like 1 Sal-Like 1 (Drosophila) HEL-S-89 HSal1 SAL1
Location (GRCh38)
16:51135982-51152683
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_002968.3
Sequence length
5134.0 nt
GC content
0.4981

Transcripts

ID Sequence Length GC content
NM_001127892.2 NCBI
CUUUGGAGGUUCAGAGCUGCAAGAAGAUGGGGACUGGUGUCGGGGCGCC… 5246 nt 0.5008
NM_002968.3 NCBI
AUUCUGCCCCAGCUGAUGUUUGAGCCAGCAUGUCGCGGAGGAAGCAAGC… 5134 nt 0.4981
Summary

The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Forensic Context

A study in mice demonstrated that the SALL1 transcript, a transcription factor, exhibited increased abundance within 0.5 hours postmortem [Pozhitkov et al. DOI:10.1098/rsob.160267].