Basic Information

Symbol
SCAND1
RNA class
mRNA
Alias
SCAN Domain Containing 1 SDP1 RAZ1 SCAN Domain-Containing Protein 1 SCAN-Related Protein RAZ1 SCAN Domain-Containing 1
Location (GRCh38)
20:35953617-35959472
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_033630.3
Sequence length
771.0 nt
GC content
0.6939

Transcripts

ID Sequence Length GC content
NM_001385710.1 NCBI
GUGACUUGCUCCUCCUUGUCUUCCACCACGAUUGUGAGGCCUCCCUAGC… 1732 nt 0.6334
NM_016558.4 NCBI
AGACGGUGUGUUGUACUUUGUCAUCGUCGCAGUAAGGCCGGUGCUAUCG… 1021 nt 0.6758
NM_033630.3 NCBI
GCAGAGAAGCCAGAGACUUUCGCUUCCGGCUGCCGCAGGCGCUUCGCUG… 771 nt 0.6939
Summary

This gene encodes a SCAN box domain-containing protein. The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. This protein binds to and may regulate the function of the transcription factor myeloid zinc finger 1B. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]

Forensic Context

A study in mouse cortical astrocytes demonstrated that carbon monoxide (CO) treatment via CORM-A1 upregulated the mRNA expression of the SCAND1 (Scand1), which was validated by qRT-PCR as part of a cytoprotective transcriptional response involving 162 differentially expressed genes [Oliveira et al. DOI:10.1007/S12035-018-1302-7].