Basic Information

Symbol
SDF2L1
RNA class
mRNA
Alias
Stromal Cell Derived Factor 2 Like 1 PWP1-Interacting Protein 8 Stromal Cell-Derived Factor 2-Like Protein 1 Dihydropyrimidinase-Like 2 SDF2-Like Protein 1 OTTHUMT00000075032 AP000553.C22.4 Stromal Cell-Derived Factor 2-Like 1 SDF2-Like 1
Location (GRCh38)
22:21642302-21644299
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_022044.3
Sequence length
825.0 nt
GC content
0.6509

Transcripts

ID Sequence Length GC content
NM_022044.3 NCBI
CCCUGGGCCCGAGGGGCUGGAGCCGGGCCGGGGCGAUGUGGAGCGCGGG… 825 nt 0.6509
Summary

Enables misfolded protein binding activity. Involved in chaperone cofactor-dependent protein refolding. Located in endoplasmic reticulum. Part of protein folding chaperone complex. [provided by Alliance of Genome Resources, Apr 2025]

Forensic Context

A study in mice demonstrated that the SDF2L1 was downregulated in the ileum of methamphetamine-treated animals compared to saline-treated controls, identifying it as one of 326 differentially expressed genes associated with a methamphetamine-induced inflammatory bowel disease model [Sun et al. DOI:10.21037/Atm-20-7741].