Basic Information
Symbol
SDF2L1
RNA class
mRNA
Alias
Stromal Cell Derived Factor 2 Like 1
PWP1-Interacting Protein 8
Stromal Cell-Derived Factor 2-Like Protein 1
Dihydropyrimidinase-Like 2
SDF2-Like Protein 1
OTTHUMT00000075032
AP000553.C22.4
Stromal Cell-Derived Factor 2-Like 1
SDF2-Like 1
Location (GRCh38)
22:21642302-21644299
Forensic tag(s)
Drug abuse diagnoses
MANE select
Transcript ID
NM_022044.3
Sequence length
825.0 nt
GC content
0.6509
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-385.20 kcal/mol
Thermodynamic ensemble
Free energy:
-398.51 kcal/mol
Frequency:
0.0000
Diversity:
238.11
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
........((((..(((((..(((((((((....(((((.(.(((..(((((((((((((((.((..((((((..((.(((.(((((((((((((((...)))))).))))))))).))).))..))))))..))))))...((((....))))((((((((......)))....))))).)))).))))))).....))).).))))).....))).))))))..))))).....)))).(((((((((...((((((....))))))..((((((((((.(((((((((.(((((((.....))))...)))))))))))))))))).)))).(.(((.(((.(((...)))))).))).)(((((((((...((((((.(((.(.(((((.(((((((((((((((((....(((((..((...((((((((..........))))))))))..))))).....))))))))).)).((.(((((((...((((((((((.((....))..))))))))))..)))((((.((.((((...(((((.....)))))...))))...))..))))(((((((((((........)))))))).))).)))).))((.(((((((....(((((....)))))((.(((.(((.(((........))).)))))).))..(((((((...)).)).))).)))))))..)))))))).)).))).).)))))))))(((((.((((((((.(((.((((....))))...))).)))))))).)))))....)))))..)))).......))))))))).....
Thermodynamic Ensemble Prediction
,(((.(,{((,|,}|(({{..(((((((({,.,.{{{((,({({({{(((({({((((({((,((,,((((((,,((,(({,((((((((((({{((,,.}}}}}}},||||||||,|}}.}}.,|}||||..}}|||}|.,((((....))))||{|||{,.,,,,.)),....))))),)))),|||}}}}}}.}})))}).,}}}}.....))).}))))),,)))))..},,,})},{||||||{{...((((((....))))))..{{((((((((.((((((((({{((((((.....)))).,})}}))))))))))))))).))}|||,|||,{||||{,,|}}},))).}}}})||{|{{{{{...((((((.(((.(.(((((.(((((((((((((((((....(((((..((...((((((((.,.....}..))))))))))..))))).....))))))))).)).((,((({,{|||,((((((((((,((....)).,)))))))))).,||,((((.((,((((...(((((.....)))))...))))...))..))))|||((((((((........)))))))),|}}.}}}).))|..(((((((....{((((...,)}})}{,.({{.{{{,(((...|||,.}}},}}}}}}.))}}|||||{,.|,}),,,,}}}.)))))))..,,)))))).)).))).).)))))))))(((((.((((((((.(((,((({....)))}...))).)))))))).))))),...})))},,|}}|.,,,...,}}))))))..,,.
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| CCCUGGGCCCGAGGGGCUGGAGCCGGGCCGGGGCGAUGUGGAGCGCGGG… | 825 nt | 0.6509 |
Summary
Enables misfolded protein binding activity. Involved in chaperone cofactor-dependent protein refolding. Located in endoplasmic reticulum. Part of protein folding chaperone complex. [provided by Alliance of Genome Resources, Apr 2025]
Forensic Context
A study in mice demonstrated that the SDF2L1 was downregulated in the ileum of methamphetamine-treated animals compared to saline-treated controls, identifying it as one of 326 differentially expressed genes associated with a methamphetamine-induced inflammatory bowel disease model [Sun et al. DOI:10.21037/Atm-20-7741].