Basic Information

Symbol
SDF4
RNA class
mRNA
Alias
Stromal Cell Derived Factor 4 Cab45 45 KDa Calcium-Binding Protein SDF-4 Stromal Cell-Derived Factor 4 Calcium Binding Protein CAB45
Location (GRCh38)
1:1216887-1238870
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_016176.6
Sequence length
1933.0 nt
GC content
0.6332

Transcripts

ID Sequence Length GC content
NM_016176.6 NCBI
GCACCGCCCCCGCCCGCAAGAAAGAUGGCAGUGGCCUGAUCCGGGCCCG… 1933 nt 0.6332
NM_016547.3 NCBI
GCACCGCCCCCGCCCGCAAGAAAGAUGGCAGUGGCCUGAUCCGGGCCCG… 2049 nt 0.6354
Summary

This gene encodes a stromal cell derived factor that is a member of the CREC protein family. The encoded protein contains six EF-hand motifs and calcium-binding motifs. This protein localizes to the Golgi lumen and may be involved in regulating calcium dependent cellular activities. [provided by RefSeq, Sep 2011]

Forensic Context

A study in humans using integrative machine learning on multi-level molecular data from monozygotic twin pairs identified that the SDF4 gene, specifically at a CpG site, exhibited increased methylation in heavier twins who consumed more sucrose, associating it with dietary patterns in the context of obesity [Kibble et al. DOI:10.1098/rsos.200872].