Basic Information

Symbol
SDS
RNA class
mRNA
Alias
Serine Dehydratase SDH L-Serine Dehydratase/L-Threonine Deaminase Hepatic Serine Dehydratase L-Threonine Dehydratase L-Serine Ammonia-Lyase L-Serine Deaminase HSDH TDH L-Serine Dehydratase EC 4.3.1.17 EC 4.3.1.19
Location (GRCh38)
12:113392423-113426301
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_006843.3
Sequence length
1605.0 nt
GC content
0.5813

Transcripts

ID Sequence Length GC content
NM_006843.3 NCBI
GACCAUUCAGAAGACUGUCCACCCGUCCUCAGCCCCCUCUCUUCGUGGG… 1605 nt 0.5813
Summary

This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008]

Forensic Context

No relevant information is available at the moment.