Basic Information

Symbol
SEC14L4
RNA class
mRNA
Alias
SEC14 Like Lipid Binding 4 TAP3 Tocopherol-Associated Protein 3 SEC14-Like Protein 4 DJ130H16.5 SEC14-Like 4 (S. Cerevisiae) SEC14-Like Lipid Binding 4 SEC14p-Like Protein TAP3 SEC14-Like 4
Location (GRCh38)
22:30488902-30505711
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_174977.4
Sequence length
2510.0 nt
GC content
0.5637

Transcripts

ID Sequence Length GC content
NM_001161368.3 NCBI
ACAACCAGGCGGCAGCGGAUACAAGGCCAGGCGGCGGCGGGCGGGCGGA… 2085 nt 0.5626
NM_174977.4 NCBI
ACAACCAGGCGGCAGCGGAUACAAGGCCAGGCGGCGGCGGGCGGGCGGA… 2510 nt 0.5637
Summary

The protein encoded by this gene is highly similar to the protein encoded by the Saccharomyces cerevisiae SEC14 gene. The SEC14 protein is a phophatidylinositol transfer protein that is essential for biogenesis of Golgi-derived transport vesicles, and thus is required for the export of yeast secretory proteins from the Golgi complex. The specific function of this protein has not yet been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009]

Forensic Context

A study in humans demonstrated that the SEC14L4 exhibited a Gini impurity score of 0 for body fluid classification, being present in some pure peripheral blood samples but absent in all tested mixtures containing blood and in mixtures without blood [Shehata et al. DOI:10.1016/j.fsigen.2025.103343].