SEC23 Homolog B, COPII Component
SEC23 Homolog B, COPII Coat Complex Component
CDA-II
HEMPAS
CDAII
Protein Transport Protein Sec23B
SEC23-Related Protein B
HSec23B
CDAN2
Congenital Dyserythropoietic Anemia, Type II
SEC23 Homolog B, Coat Complex II Component
Sec23 (S. Cerevisiae) Homolog B
Sec23 Homolog B (S. Cerevisiae)
Transport Protein SEC23B
SEC23-Like Protein B
CWS7
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
Forensic Context
A study in mice demonstrated that chronic methamphetamine administration significantly upregulated the SEC23B gene in oligodendrocytes, which is involved in the protein processing of endoplasmic reticulum pathway [Oladapo et al. DOI:10.3390/Ijms26020649].