Basic Information

Symbol
SELENBP1
RNA class
mRNA
Alias
Selenium Binding Protein 1 Methanethiol Oxidase HSBP LPSB 56 KDa Selenium-Binding Protein HSP56 SBP56 SP56 MTO Epididymis Secretory Sperm Binding Protein Li 134P Selenium-Binding Protein 1 HEL-S-134P EC 1.8.3.4 EHMTO SBP
Location (GRCh38)
1:151364302-151372716
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003944.4
Sequence length
1722.0 nt
GC content
0.5708

Transcripts

ID Sequence Length GC content
NM_001258288.2 NCBI
GGAACAGCGGCCUCUGACACCAGCACAGCAAACCCGCCGGGAUCAAAGU… 1536 nt 0.5658
NM_001258289.2 NCBI
GGAACAGCGGCCUCUGACACCAGCACAGCAAACCCGCCGGGAUCAAAGU… 1931 nt 0.5805
NM_003944.4 NCBI
GGAACAGCGGCCUCUGACACCAGCACAGCAAACCCGCCGGGAUCAAAGU… 1722 nt 0.5708
Summary

This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]

Forensic Context

A study in humans demonstrated that the SELENBP1 shows high sensitivity and specificity rates in cases of death caused by coronary artery spasm [Cătinas et al. DOI:10.3390/ijms26146818]. A study in humans demonstrated that the SELENBP1 shows high sensitivity and specificity rates in cases of death caused by coronary artery spasm [Cătinas and Hostiuc DOI:10.3390/ijms26146818].