Basic Information

Symbol
SERBP1
RNA class
mRNA
Alias
SERPINE1 MRNA Binding Protein 1 PAI-RBP1 PAIRBP1 CGI-55 CHD3IP HABP4L Hero45 Plasminogen Activator Inhibitor 1 RNA-Binding Protein SERPINE1 MRNA-Binding Protein 1 PAI1 RNA-Binding Protein 1 DKFZP564M2423 Chromodomain Helicase DNA Binding Protein 3 Interacting Protein PAI-1 MRNA Binding Protein
Location (GRCh38)
1:67407810-67430415
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001018069.2
Sequence length
6681.0 nt
GC content
0.3815

Transcripts

ID Sequence Length GC content
NM_001018067.2 NCBI
CUCUCUCGGCCCGGCCAUCUUGUGGGAAGAGCUGAAGCAGGCGCUCUUG… 6726 nt 0.3811
NM_001018068.2 NCBI
CUCUCUCGGCCCGGCCAUCUUGUGGGAAGAGCUGAAGCAGGCGCUCUUG… 6708 nt 0.3813
NM_001018069.2 NCBI
CUCUCUCGGCCCGGCCAUCUUGUGGGAAGAGCUGAAGCAGGCGCUCUUG… 6681 nt 0.3815
NM_015640.4 NCBI
CUCUCUCGGCCCGGCCAUCUUGUGGGAAGAGCUGAAGCAGGCGCUCUUG… 6663 nt 0.3818
Summary

Enables several functions, including SUMO binding activity; mRNA 3'-UTR binding activity; and ribosome binding activity. Involved in PML body organization and ribosome hibernation. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A review of forensic proteomics literature notes that the SERBP1 is identified as a protein marker whose abundance increases post-mortem in early post-mortem interval (PMI) estimation studies using skeletal muscle tissue from human and animal models [Alex et al. DOI:10.1016/j.scijus.2025.101320].