Basic Information

Symbol
SH2D5
RNA class
mRNA
Alias
SH2 Domain Containing 5 SH2 Domain-Containing Protein 5
Location (GRCh38)
1:20719724-20732837
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl UniProt GTEx

MANE select

Transcript ID
NM_001103161.2
Sequence length
3898.0 nt
GC content
0.6175

Transcripts

ID Sequence Length GC content
NM_001103160.2 NCBI
AGUUCCCGGCUGAGAACGUCCCGGCAGGAAGAAAGUGAGGAGGAGGAUG… 3769 nt 0.6137
NM_001103161.2 NCBI
AGUUCCCGGCUGAGAACGUCCCGGCAGGAAGAAAGUGAGGAGGAGGAUG… 3898 nt 0.6175
Summary

Predicted to be located in synapse. Predicted to be active in postsynaptic density. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans and rats demonstrated that ultraviolet-B irradiation induces significant transcriptional changes in skin, with the SH2D5 being the most up-regulated gene in human skin (fold change 196.3) and also substantially up-regulated in rat skin (fold change 51.4) at the peak of hyperalgesia [Dawes et al. DOI:10.1371/journal.pone.0093338].