Basic Information

Symbol
SLAIN2
RNA class
mRNA
Alias
SLAIN Motif Family Member 2 KIAA1458 SLAIN Motif-Containing Protein 2 FLJ21611
Location (GRCh38)
4:48341472-48426201
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Chronological age estimation
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_020846.2
Sequence length
6081.0 nt
GC content
0.3906

Transcripts

ID Sequence Length GC content
NM_020846.2 NCBI
AAUCCCGGAGCCGGCGCAGAUGAGGCAGUUCGGCUGGGGCCAGCGGCGC… 6081 nt 0.3906
Summary

Involved in cytoplasmic microtubule organization; microtubule nucleation; and positive regulation of microtubule polymerization. Located in centrosome; cytosol; and microtubule plus-end. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans identified the SLAIN2 as an mRNA marker for age estimation, demonstrating its expression decreases with age in dried blood stain RNA-Seq data [Dørum et al. DOI:10.1016/j.fsigen.2023.102976]. This marker was part of a lasso regression-selected gene list that achieved a mean absolute error of 4.46 years for age prediction in the primary dataset, establishing its utility in a forensic mRNA assay for predicting a biological stain donor's chronological age.