Basic Information

Symbol
SLC11A2
RNA class
mRNA
Alias
Solute Carrier Family 11 Member 2 DMT-1 DCT1 DMT1 Natural Resistance-Associated Macrophage Protein 2 Divalent Cation Transporter 1 NRAMP2 Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporter), Member 2 Divalent Metal Transporter 1 FLJ37416 NRAMP 2 Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 AHMIO1
Location (GRCh38)
12:50979401-51028566
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_000617.3
Sequence length
4132.0 nt
GC content
0.4308

Transcripts

ID Sequence Length GC content
NM_001379455.1 NCBI
CUUUUCCAUCAGGCACCAAGUCCGGAGUUUGCGUGGCUCUGAUGUCUGC… 4668 nt 0.4359
NM_001414744.1 NCBI
AGCGUGGCGCUGGCUCCCGGAAUAUGGAGCCCUGGGCGCGGGGGCGGCG… 3839 nt 0.4423
NM_001414745.1 NCBI
AGCGUGGCGCUGGCUCCCGGAAUAUGGAGCCCUGGGCGCGGGGGCGGCG… 4769 nt 0.4603
NM_001414746.1 NCBI
AGCGUGGCGCUGGCUCCCGGAAUAUGGAGCCCUGGGCGCGGGGGCGGCG… 3844 nt 0.4422
NM_001414747.1 NCBI
AGCGUGGCGCUGGCUCCCGGAAUAUGGAGCCCUGGGCGCGGGGGCGGCG… 3677 nt 0.4408
NM_001414748.1 NCBI
AGCGUGGCGCUGGCUCCCGGAAUAUGGAGCCCUGGGCGCGGGGGCGGCG… 4047 nt 0.4299
NM_001414749.1 NCBI
GCAGCUUCAGAGUUUAGCCUGAACUGUGGCAGGAUUUUGUAACUUGCAC… 4004 nt 0.4238
NM_001414750.1 NCBI
GCAGCUUCAGAGUUUAGCCUGAACUGUGGCAGGAUUUUGUAACUUGCAC… 4325 nt 0.4229
Showing 11 to 18 of 18 entries
Summary

This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]

Forensic Context

No relevant information is available at the moment.