Basic Information

Symbol
SLC12A7
RNA class
mRNA
Alias
Solute Carrier Family 12 Member 7 KCC4 Solute Carrier Family 12 (Potassium/Chloride Transporter), Member 7 Electroneutral Potassium-Chloride Cotransporter 4 K-Cl Cotransporter 4 DKFZP434F076 Solute Carrier Family 12 (Potassium/Chloride Transporters), Member 7 Potassium/Chloride Transporter KCC4 SUCO/SLC12A7 Fusion
Location (GRCh38)
5:1050384-1155916
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_006598.3
Sequence length
5300.0 nt
GC content
0.6111

Transcripts

ID Sequence Length GC content
NM_006598.3 NCBI
AGUCCCGUGGCGUCGGCGGGAGCGGCGCAGCGCGGGCCGGGCCGGGACG… 5300 nt 0.6111
Summary

Enables protein kinase binding activity. Predicted to be involved in several processes, including chloride ion homeostasis; monoatomic ion transmembrane transport; and potassium ion homeostasis. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that chronic alcohol exposure significantly upregulated the SLC12A7 mRNA in hippocampal tissue, as identified through high-throughput sequencing and bioinformatic network analysis [Du et al. DOI:10.3389/fphar.2024.1377501].