Basic Information

Symbol
SLC14A2
RNA class
mRNA
Alias
Solute Carrier Family 14 Member 2 HUT2 UT2 Solute Carrier Family 14 (Urea Transporter), Member 2 Urea Transporter, Kidney Urea Transporter 2 HUT-A6 UT-A2 UTA UTR
Location (GRCh38)
18:45212995-45683688
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_007163.4
Sequence length
4073.0 nt
GC content
0.5220

Transcripts

ID Sequence Length GC content
NM_001242692.2 NCBI
GUAAGCUGCCUCCAUCAUCCUAAAAAACGACCAUGCUGAAAGAGCUCCU… 4253 nt 0.5159
NM_001371319.1 NCBI
AUUUGUAUAAUUGUGAGCUUGGUAGAGGCAUCAUUGCAGAUCUGCUACU… 4649 nt 0.5066
NM_007163.4 NCBI
ACACCAUCUCUCUCUUCUGCCGCCAUUUGAGAAGGUCCAAGUUUGCUUC… 4073 nt 0.5220
Summary

The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]

Forensic Context

A study in zebrafish demonstrated that the SLC14A2 transcript, a urea transporter, increased in abundance at 24 hours postmortem [Pozhitkov et al. DOI:10.1098/rsob.160267].