Basic Information

Symbol
SLC15A3
RNA class
mRNA
Alias
Solute Carrier Family 15 Member 3 PHT2 Solute Carrier Family 15 (Oligopeptide Transporter), Member 3 Peptide/Histidine Transporter 2 Osteoclast Transporter Peptide Transporter 3 HPTR3 HPHT2 OCTP PTR3 Solute Carrier Family 15, Member 3
Location (GRCh38)
11:60937060-60952653
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_016582.3
Sequence length
2506.0 nt
GC content
0.6441

Transcripts

ID Sequence Length GC content
NM_016582.3 NCBI
AGAGUUUCUCAAGAAGCCGAGAGAGGGACAGAGGCUGAGCCUGGGGGGA… 2506 nt 0.6441
Summary

Enables dipeptide transmembrane transporter activity. Involved in dipeptide import across plasma membrane. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2025]

Forensic Context

A study in mice demonstrated that the SLC15A3 gene was upregulated in blood leukocytes at 2 hours post-injury as a common early transcriptional response across three distinct models of systemic inflammation: trauma/hemorrhage, burn injury, and lipopolysaccharide infusion [Brownstein et al. DOI:10.1152/physiolgenomics.00213.2005].