Basic Information

Symbol
SLC1A7
RNA class
mRNA
Alias
Solute Carrier Family 1 Member 7 EAAT5 Excitatory Amino Acid Transporter 5 Solute Carrier Family 1 (Glutamate Transporter), Member 7 Retinal Glutamate Transporter Excitatory Amino Acid Transporter 5 (Retinal Glutamate Transporter) AAAT
Location (GRCh38)
1:53087179-53142638
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_006671.6
Sequence length
2698.0 nt
GC content
0.6012

Transcripts

ID Sequence Length GC content
NM_001287595.2 NCBI
GGUAAUAGGAUUGUGGCUUCCCUCUAAGGCGGCCACACGGGCAUGGCCG… 2875 nt 0.6052
NM_001287596.2 NCBI
GGUAAUAGGAUUGUGGCUUCCCUCUAAGGCGGCCACACGGGCAUGGCCG… 1327 nt 0.5381
NM_001287597.2 NCBI
GGUAAUAGGAUUGUGGCUUCCCUCUAAGGCGGCCACACGGGCAUGGCCG… 2501 nt 0.5994
NM_006671.6 NCBI
GGUAAUAGGAUUGUGGCUUCCCUCUAAGGCGGCCACACGGGCAUGGCCG… 2698 nt 0.6012
Summary

Enables glutamate:sodium symporter activity. Involved in neurotransmitter uptake. Predicted to be located in photoreceptor cell terminal bouton. Predicted to be active in glutamatergic synapse; postsynaptic membrane; and presynaptic membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans identified ENST00000620347.4 as a down-regulated mRNA in peripheral blood mononuclear cells of ST-elevation myocardial infarction patients compared to non-ST-elevation myocardial infarction patients, with a fold change of 3.88, and classified it as a diagnostic biomarker for acute myocardial infarction [Zhong et al. DOI:10.1097/MD.0000000000013066].