Basic Information

Symbol
SLC20A1
RNA class
mRNA
Alias
Solute Carrier Family 20 Member 1 PiT-1 Gibbon Ape Leukemia Virus Receptor 1 Glvr-1 GLVR1 PiT1 Solute Carrier Family 20 (Phosphate Transporter), Member 1 Sodium-Dependent Phosphate Transporter 1 Leukemia Virus Receptor 1 Homolog Phosphate Transporter 1 GLVR-1 PIT1
Location (GRCh38)
2:112645854-112663829
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_005415.5
Sequence length
3297.0 nt
GC content
0.4625

Transcripts

ID Sequence Length GC content
NM_005415.5 NCBI
GGAGUGAUGGCUGCCGGCGCUCUCUGCGUGGUUCUUCUUCUCGGCCGCU… 3297 nt 0.4625
Summary

The protein encoded by this gene is a sodium-phosphate symporter that absorbs phosphate from interstitial fluid for use in cellular functions such as metabolism, signal transduction, and nucleic acid and lipid synthesis. The encoded protein is also a retroviral receptor, causing human cells to be susceptible to infection by gibbon ape leukemia virus, simian sarcoma-associated virus, feline leukemia virus subgroup B, and 10A1 murine leukemia virus.[provided by RefSeq, Mar 2011]

Forensic Context

A study in rhesus macaques identified the SLC20A1 as a shared upregulated differentially expressed gene in left ventricular tissue between adult human and rhesus macaque hypertrophic cardiomyopathy [Rivas et al. DOI:10.1038/s41598-024-82770-4].