Basic Information

Symbol
SLC24A3
RNA class
mRNA
Alias
Solute Carrier Family 24 Member 3 Solute Carrier Family 24 (Sodium/Potassium/Calcium Exchanger), Member 3 Sodium/Potassium/Calcium Exchanger 3 Na(+)/K(+)/Ca(2+)-Exchange Protein 3 NCKX3 Sodium Calcium Exchanger
Location (GRCh38)
20:19212510-19722926
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_020689.4
Sequence length
3922.0 nt
GC content
0.5352

Transcripts

ID Sequence Length GC content
NM_020689.4 NCBI
GAUAGCGACGAGGAGGGCGACGACGAGGAGACGGGCAGCGGCGAGGAGG… 3922 nt 0.5352
Summary

Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008]

Forensic Context

A study in humans demonstrated that the SLC24A3 was downregulated in subcutaneous adipose tissue during short-term (0-5 month) weight loss in obese participants [Bollepalli et al. DOI:10.1038/ijo.2017.245].