Basic Information

Symbol
SLC24A4
RNA class
mRNA
Alias
Solute Carrier Family 24 Member 4 NCKX4 Solute Carrier Family 24 (Sodium/Potassium/Calcium Exchanger), Member 4 Sodium/Potassium/Calcium Exchanger 4 Na(+)/K(+)/Ca(2+)-Exchange Protein 4 Na/Ca-K Exchanger 4 SLC24A2 AI2A5 SHEP6
Location (GRCh38)
14:92322581-92501481
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_153646.4
Sequence length
10388.0 nt
GC content
0.5067

Transcripts

ID Sequence Length GC content
NM_001378620.1 NCBI
AGACGCUGGCGCCCGCAGCCGAGAAGCCAGAGAGAAAGUUCCCGGGGAG… 9846 nt 0.4924
NM_153646.4 NCBI
AGACGCUGGCGCCCGCAGCCGAGAAGCCAGAGAGAAAGUUCCCGGGGAG… 10388 nt 0.5067
NM_153647.4 NCBI
AGACGCUGGCGCCCGCAGCCGAGAAGCCAGAGAGAAAGUUCCCGGGGAG… 9789 nt 0.4924
NM_153648.4 NCBI
GGGCCCGCAGAUCUCUCUGGUUCCCCUCUCUGCCCCGUCUCCAGCUUUU… 9647 nt 0.4874
Summary

This gene encodes a sodium/potassium/calcium exchange protein. The encoded antiporter transports one calcium and one potassium ion in exchange for four sodium ions and has been implicated in amelogenesis and enamel maturation. Certain variants in this gene have been associated with skin, hair, and eye pigmentation, while other variants have been identified in people with hypomaturation-type amelogenesis imperfecta. [provided by RefSeq, Nov 2023]

Forensic Context

No relevant information is available at the moment.