Basic Information

Symbol
SLC26A2
RNA class
mRNA
Alias
Solute Carrier Family 26 Member 2 DTDST DTD Solute Carrier Family 26 (Sulfate Transporter), Member 2 Solute Carrier Family 26 (Anion Exchanger), Member 2 Diastrophic Dysplasia Protein Sulfate Transporter Diastrophic Dysplasia Sulfate Transporter Sulfate Anion Transporter 1 Diastrophic Dysplasia D5S1708 MSTP157 MST153 EDM4
Location (GRCh38)
5:149960758-149993455
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_000112.4
Sequence length
8054.0 nt
GC content
0.3957

Transcripts

ID Sequence Length GC content
NM_000112.4 NCBI
GUUUACACUGGCUCUGCCUCCGGCAUCUCUUCGCCGGUGCGUCCUCGCC… 8054 nt 0.3957
Summary

The diastrophic dysplasia sulfate transporter is a transmembrane glycoprotein implicated in the pathogenesis of several human chondrodysplasias. It apparently is critical in cartilage for sulfation of proteoglycans and matrix organization. [provided by RefSeq, Jul 2008]

Forensic Context

A study in human keratinocytes and mouse skin demonstrated that X-ray irradiation (5 Gy) significantly downregulated the SLC26A2 gene expression to 0.65-fold in keratinocytes 3 hours post-irradiation [Koike et al. DOI:10.1269/jrr.46.173].