Solute Carrier Family 31 Member 2
HCTR2
CTR2
Copper Transporter 2
COPT2
Solute Carrier Family 31 (Copper Transporter), Member 2
Protein SLC31A2
Solute Carrier Family 31 (Copper Transporters), Member 2
Probable Low Affinity Copper Uptake Protein 2
Enables copper ion transmembrane transporter activity. Involved in copper ion import. Located in late endosome membrane; lysosomal membrane; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in domestic swine demonstrated that the SLC31A2 exhibited opposite regulation in myocardial infarction, showing induction in the border zone but repression in the ischemic zone of the heart [Kaikkonen et al. DOI:10.1161/CIRCGENETICS.117.001702]. In a separate single-cell transcriptomic analysis of radiation-induced lung injury in rats, the SLC31A2 was identified as an orthologous gene associated with inflammatory processes [Shi et al. DOI:10.17305/bb.2024.10357].