Basic Information

Symbol
SLC31A2
RNA class
mRNA
Alias
Solute Carrier Family 31 Member 2 HCTR2 CTR2 Copper Transporter 2 COPT2 Solute Carrier Family 31 (Copper Transporter), Member 2 Protein SLC31A2 Solute Carrier Family 31 (Copper Transporters), Member 2 Probable Low Affinity Copper Uptake Protein 2
Location (GRCh38)
9:113150976-113164140
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001860.3
Sequence length
1723.0 nt
GC content
0.4689

Transcripts

ID Sequence Length GC content
NM_001860.3 NCBI
GAACUGACUCGGAGCGAGGAGACCCGAGCGAGCAGACGCGGCCCUGGCG… 1723 nt 0.4689
Summary

Enables copper ion transmembrane transporter activity. Involved in copper ion import. Located in late endosome membrane; lysosomal membrane; and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in domestic swine demonstrated that the SLC31A2 exhibited opposite regulation in myocardial infarction, showing induction in the border zone but repression in the ischemic zone of the heart [Kaikkonen et al. DOI:10.1161/CIRCGENETICS.117.001702]. In a separate single-cell transcriptomic analysis of radiation-induced lung injury in rats, the SLC31A2 was identified as an orthologous gene associated with inflammatory processes [Shi et al. DOI:10.17305/bb.2024.10357].