Basic Information

Symbol
SLC35H1
RNA class
mRNA
Alias
Solute Carrier Family 35 Member H1 Solute Carrier Family 35 Member C2 BA394O2.1 C20orf5 CGI-15 OVCOV1 Solute Carrier Family 35 (GDP-Fucose Transporter), Member C2 Ovarian Cancer-Overexpressed Gene 1 Protein SLC35C2 Solute Carrier Family 35, Member C2 Ovarian Cancer Overexpressed 1 SLC35H1
Location (GRCh38)
20:46345980-46364458
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_015945.12
Sequence length
5820.0 nt
GC content
0.5467

Transcripts

ID Sequence Length GC content
NM_001281457.2 NCBI
AUCCGGCCUCGCACUUCCGGUGGGGAGAUUCCGGCCUGGAGCUCCCAGG… 5749 nt 0.5464
NM_001281458.2 NCBI
AUCCGGCCUCGCACUUCCGGUGGGGAGAUUCCGGCCUGGAGCUCCCAGG… 5688 nt 0.5466
NM_001281459.2 NCBI
AUCCGGCCUCGCACUUCCGGUGGGGAGAUUCCGGCCUGGAGCUCCCAGG… 5686 nt 0.5454
NM_001281460.2 NCBI
AUCCGGCCUCGCACUUCCGGUGGGGAGAUUCCGGCCUGGAGCUCCCAGG… 6152 nt 0.5458
NM_015945.12 NCBI
AUCCGGCCUCGCACUUCCGGUGGGGAGAUUCCGGCCUGGAGCUCCCAGG… 5820 nt 0.5467
NM_173073.4 NCBI
AUCCGGCCUCGCACUUCCGGUGGGGAGAUUCCGGCCUGGAGCUCCCAGG… 5757 nt 0.5458
NM_173179.4 NCBI
AUCCGGCCUCGCACUUCCGGUGGGGAGAUUCCGGCCUGGAGCUCCCAGG… 6015 nt 0.5485
Summary

This gene encodes a member of the triose-phosphate transporter protein family. This gene is regulated by oxygen tension, is induced in hypoxic trophoblast cells, and is overexpressed in ovarian cancer. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Jul 2013]

Forensic Context

A study in rats demonstrated that the SLC35H1 is a brain transcript whose expression is negatively correlated with voluntary alcohol consumption and positively correlated with the hub lncRNA Lrap [Saba et al. DOI:10.1111/gbb.12698]. A study in rats demonstrated that the long non-coding RNA Lrap is a hub gene in a brain co-expression module associated with voluntary alcohol consumption, where its disruption via CRISPR/Cas9 knockout significantly increased alcohol intake and altered the expression and splicing of over 700 other brain transcripts [Saba et al. DOI:10.1111/Gbb.12698].