Basic Information

Symbol
SLC43A3
RNA class
mRNA
Alias
Solute Carrier Family 43 Member 3 SEEEG-1 FOAP-13 PRO1659 Eeg1 Likely Ortholog Of Mouse Embryonic Epithelial Gene 1 Equilibrative Nucleobase Transporter 1 DKFZp762A227 ENBT1 Solute Carrier Family 43, Member 3 Protein FOAP-13
Location (GRCh38)
11:57406954-57429035
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_199329.3
Sequence length
2619.0 nt
GC content
0.5273

Transcripts

ID Sequence Length GC content
NM_001278201.2 NCBI
GCGAAUGCGAACCUGGCCCGUGCGGAAAGGGCGCGGAGAGCCCCGGCGC… 2652 nt 0.5260
NM_001278206.2 NCBI
GCGAAUGCGAACCUGGCCCGUGCGGAAAGGGCGCGGAGAGCCCCGGCGC… 2695 nt 0.5265
NM_014096.4 NCBI
GCGAAUGCGAACCUGGCCCGUGCGGAAAGGGCGCGGAGAGCCCCGGCGC… 2795 nt 0.5417
NM_017611.3 NCBI
GCUCUGGGAGUGUGAAACUGGGAGAGACGGUUAAGCUGGGGACGGUAUU… 2597 nt 0.5221
NM_199329.3 NCBI
GCGAAUGCGAACCUGGCCCGUGCGGAAAGGGCGCGGAGAGCCCCGGCGC… 2619 nt 0.5273
Summary

Enables adenine transmembrane transporter activity; guanine transmembrane transporter activity; and xenobiotic transmembrane transporter activity. Involved in hypoxanthine transport. Located in basolateral plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in rhesus macaques identified the SLC43A3 as a shared upregulated differentially expressed gene in left ventricular tissue from animals with hypertrophic cardiomyopathy compared to pediatric human cases [Rivas et al. DOI:10.1038/s41598-024-82770-4].