Basic Information

Symbol
SLC5A10
RNA class
mRNA
Alias
Solute Carrier Family 5 Member 10 SGLT5 Solute Carrier Family 5 (Sodium/Glucose Cotransporter), Member 10 Solute Carrier Family 5 (Sodium/Sugar Cotransporter), Member 10 Sodium/Mannose Cotransporter SLC5A10 Sodium/Glucose Cotransporter 5 Na(+)/Glucose Cotransporter 5 SGLT-5
Location (GRCh38)
17:18950345-19022595
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001042450.4
Sequence length
3966.0 nt
GC content
0.6049

Transcripts

ID Sequence Length GC content
NM_001042450.4 NCBI
AGUCCCUCGGGCUCAUACCUAGUGCCUGCGGCAGGACAGCCAUGGCCGC… 3966 nt 0.6049
NM_001270648.3 NCBI
AGUCCCUCGGGCUCAUACCUAGUGCCUGCGGCAGGACAGCCAUGGCCGC… 3885 nt 0.6051
NM_001270649.2 NCBI
AGUCCCUCGGGCUCAUACCUAGUGCCUGCGGCAGGACAGCCAUGGCCGC… 3858 nt 0.6032
NM_001282417.1 NCBI
CUAGUCCUGUAUGUGAGGACUAUUAAUUGUUUUUUGUUGUUGUUGUUGU… 2201 nt 0.5915
NM_152351.6 NCBI
AGUCCCUCGGGCUCAUACCUAGUGCCUGCGGCAGGACAGCCAUGGCCGC… 4014 nt 0.6039
Summary

This gene is a member of the sodium/glucose transporter family. Members of this family are sodium-dependent transporters and can be divided into two subfamilies based on sequence homology, one that co-transports sugars and the second that transports molecules such as ascorbate, choline, iodide, lipoate, monocaroboxylates, and pantothenate. The protein encoded by this gene has the highest affinity for mannose and has been reported to be most highly expressed in the kidney. This protein may function as a kidney-specific, sodium-dependent mannose and fructose co-transporter. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

Forensic Context

A study in mice demonstrated that the SLC5A10 transcript, a carbohydrate transporter, increased in relative abundance within 0.5 hours postmortem [Pozhitkov et al. DOI:10.1098/rsob.160267].