Basic Information

Symbol
SLC5A8
RNA class
mRNA
Alias
Solute Carrier Family 5 Member 8 AIT Solute Carrier Family 5 (Sodium/Monocarboxylate Cotransporter), Member 8 Solute Carrier Family 5 (Iodide Transporter), Member 8 Electrogenic Sodium Monocarboxylate Cotransporter Sodium-Coupled Monocarboxylate Transporter 1 Sodium Iodide-Related Cotransporter Apical Iodide Transporter SMCT1 SMCT
Location (GRCh38)
12:101155493-101210238
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_145913.5
Sequence length
4009.0 nt
GC content
0.4368

Transcripts

ID Sequence Length GC content
NM_145913.5 NCBI
GAACAAAACCUGCCCAGAGCGCUCCCUGUGUAGAUUCGCUGGAAGCAGC… 4009 nt 0.4368
Summary

SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions as a high-affinity sodium-coupled lactate transporter involved in reabsorption of lactate and maintenance of blood lactate levels (Thangaraju et al., 2006 [PubMed 16873376]).[supplied by OMIM, Dec 2008]

Forensic Context

No relevant information is available at the moment.