Basic Information

Symbol
SLC6A14
RNA class
mRNA
Alias
Solute Carrier Family 6 Member 14 Sodium- And Chloride-Dependent Neutral And Basic Amino Acid Transporter B(0+) Solute Carrier Family 6 (Neurotransmitter Transporter), Member 14 Solute Carrier Family 6 (Amino Acid Transporter), Member 14 Amino Acid Transporter ATB0+ Amino Acid Transporter B0+ BMIQ11
Location (GRCh38)
X:116436606-116461458
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_007231.5
Sequence length
4536.0 nt
GC content
0.3710

Transcripts

ID Sequence Length GC content
NM_007231.5 NCBI
GGCUCACUCUGGCAGGUAGGAACAGGGGAGAGUGCACCUGCUACCAGUC… 4536 nt 0.3710
Summary

This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010]

Forensic Context

A study in humans demonstrated that within monozygotic twin pairs, the heavier co-twin had significantly higher serotonin transporter (SERT) binding in the hypothalamus/thalamus compared to the leaner co-twin, an effect driven by women [Koskela et al. DOI:10.1016/j.physbeh.2007.11.043].