Basic Information

Symbol
SLC9A2
RNA class
mRNA
Alias
Solute Carrier Family 9 Member A2 NHE2 Solute Carrier Family 9, Subfamily A (NHE2, Cation Proton Antiporter 2), Member 2 Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Member 2 Sodium/Hydrogen Exchanger 2 Na(+)/H(+) Exchanger 2 Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Isoform 2 Solute Carrier Family 9 Member 2 NHE-2
Location (GRCh38)
2:102619553-102711355
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003048.6
Sequence length
5601.0 nt
GC content
0.4413

Transcripts

ID Sequence Length GC content
NM_003048.6 NCBI
GGAGAGCAGCGCACCGGCAUGGGCAGGCGGCCGGCGGCGGAGGGCGGCU… 5601 nt 0.4413
Summary

This gene encodes a member of the sodium-hydrogen exchanger (NHE) protein family. These proteins are involved in sodium-ion transport by exchanging intracellular hydrogen ions to external sodium ions and help in the regulation of cell pH and volume. The encoded protein is localized to the apical membrane and is involved in apical absorption of sodium. [provided by RefSeq, Jun 2016]

Forensic Context

A study in mouse cardiac mesenchymal stem cells demonstrated that overexpression of HDAC11 induced transcriptional reprogramming, activating cell cycle pathways and promoting proliferation while suppressing various metabolic and transport processes [Zhang et al. DOI:10.3390/biom15050662].