Basic Information

Symbol
SLCO2A1
RNA class
mRNA
Alias
Solute Carrier Organic Anion Transporter Family Member 2A1 OATP2A1 PGT SLC21A2 Solute Carrier Family 21 (Prostaglandin Transporter), Member 2 Prostaglandin Transporter Matrin F/G 1 PHOAR2 MATR1 Solute Carrier Organic Anion Transporter Family, Member 2A1 Solute Carrier Family 21 Member 2 PHOAD
Location (GRCh38)
3:133932699-134052184
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_005630.3
Sequence length
4067.0 nt
GC content
0.5488

Transcripts

ID Sequence Length GC content
NM_005630.3 NCBI
AGUCUCCGCUCCGCGAAUCUCCUCCGGCCACUGCCGCCGCGGUCGCCUC… 4067 nt 0.5488
Summary

This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues. [provided by RefSeq, Dec 2011]

Forensic Context

A study in rhesus macaques identified the SLCO2A1 as a shared upregulated differentially expressed gene in left ventricular tissue from animals with hypertrophic cardiomyopathy compared to adult human HCM cases, establishing its association with this cardiac disease process [Rivas et al. DOI:10.1038/s41598-024-82770-4].