Basic Information

Symbol
SLURP1
RNA class
mRNA
Alias
Secreted LY6/PLAUR Domain Containing 1 ANUP ARS LY6-MT LY6LS ArsB MDM Secreted Ly-6/UPAR-Related Protein 1 Lymphocyte Antigen 6-Like Secreted Anti-Neoplastic Urinary Protein ARS(Component B)-81/S ARS Component B SLURP-1 Secreted Ly6/UPAR Related Protein 1
Location (GRCh38)
8:142740949-142742406
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_020427.3
Sequence length
527.0 nt
GC content
0.6262

Transcripts

ID Sequence Length GC content
NM_020427.3 NCBI
AUCACUUCUGAGCACGGAGCAAUGGCCUCUCGCUGGGCUGUGCAGCUGC… 527 nt 0.6262
Summary

The protein encoded by this gene is a member of the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. It is thought that this secreted protein contains antitumor activity. Mutations in this gene have been associated with Mal de Meleda, a rare autosomal recessive skin disorder. This gene maps to the same chromosomal region as several members of the Ly6/uPAR family of glycoprotein receptors. [provided by RefSeq, Jul 2008]

Forensic Context

A study in rats demonstrated that arylsulfatase B (Arsb) gene expression was significantly altered in liver tissue on day 7 following a 20% total body surface area burn injury [Jayaraman et al. DOI:10.1016/j.jss.2007.05.025].