Basic Information

Symbol
SMARCA2
RNA class
mRNA
Alias
SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 2 HBRM BRM BAF190 HSNF2a SNF2LA SNF2L2 Sth1p SNF2 SWI2 SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A, Member 2 SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 2 Probable Global Transcription Activator SNF2L2 BRG1-Associated Factor 190B Protein Brahma Homolog Brahma Homolog SNF2-Alpha SAMRCA2 BAF190B SWI/SNF-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin A2 Global Transcription Activator Homologous Sequence Putative Global Transcription Activator SNF2L2 Sucrose Nonfermenting 2-Like Protein 2 ATP-Dependent Helicase SMARCA2 SNF2/SWI2-Like Protein 2 EC 3.6.4.- EC 3.6.1 NCBRS SNF2A BIS
Location (GRCh38)
9:1980290-2193624
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003070.5
Sequence length
5748.0 nt
GC content
0.4878

Transcripts

ID Sequence Length GC content
NM_001289396.1 NCBI
UCAGAAGAAAGCCCCGAGAUCACAGAGACCCGGCGAGAUCACAGAGACC… 5879 nt 0.4863
NM_001289397.2 NCBI
GUACUCUGGGUGACUCAGAGAGGGAAGAGAUUCAGCCAGCACACUCCUC… 5520 nt 0.4877
NM_001289398.2 NCBI
GCCACAUGGCUUGGUGGACUUGGAGAGGCGGAGGUGGAAACGAUGCGCA… 1848 nt 0.4048
NM_001289399.1 NCBI
AUUCACUUCAUUAAAUCUAGAGGCAGUUGAGCAUGGGAGCCGUCUGUAU… 1833 nt 0.3961
NM_001289400.1 NCBI
ACUUCAUUAAAUCUAGAGGCAGUUGAGCAUGGGAGCCGUCUGUAUGUUG… 2254 nt 0.3926
NM_003070.5 NCBI
GUACUCUGGGUGACUCAGAGAGGGAAGAGAUUCAGCCAGCACACUCCUC… 5748 nt 0.4878
NM_139045.4 NCBI
GUACUCUGGGUGACUCAGAGAGGGAAGAGAUUCAGCCAGCACACUCCUC… 5694 nt 0.4882
Summary

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014] CIViC Summary for SMARCA2 Gene

Forensic Context

No relevant information is available at the moment.