Basic Information

Symbol
SMUG1
RNA class
mRNA
Alias
Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 HMUDG UNG3 FDG Single-Strand Selective Monofunctional Uracil DNA Glycosylase EC 3.2.2.- EC 3.2.2
Location (GRCh38)
12:54121277-54189008
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001243787.2
Sequence length
2681.0 nt
GC content
0.5099

Transcripts

ID Sequence Length GC content
NM_001243787.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGAUUAUGAGCUUACA… 2681 nt 0.5099
NM_001243788.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGACAGCGGCAUG… 2597 nt 0.5129
NM_001243789.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 2139 nt 0.5147
NM_001243790.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 2058 nt 0.5092
NM_001243791.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGACAGCGGCAUG… 1741 nt 0.4986
NM_001351237.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGCUGGAGUGCAAUG… 1823 nt 0.5047
NM_001351238.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGCAGAUUAUGAGCUU… 1828 nt 0.4951
NM_001351239.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGAUUAUGAGCUUACA… 1825 nt 0.4948
NM_001351240.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGAUUAUGAGCUUACA… 2075 nt 0.4940
NM_001351241.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 1912 nt 0.5031
Showing 1 to 10 of 31 entries
Summary

This gene encodes a protein that participates in base excision repair by removing uracil from single- and double-stranded DNA. Many alternatively spliced transcript variants exist for this gene; the full-length nature is known for some but not all of the variants. [provided by RefSeq, Aug 2011]

Forensic Context

A topographic transcriptomic analysis in mice identified SMUG1 as one of five seed transcripts with highly specific enhanced expression in the nucleus accumbens shell (NAcSh) [Crofton et al. DOI:10.1016/J.Neuropharm.2020.108398].