Basic Information

Symbol
SMUG1
RNA class
mRNA
Alias
Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 HMUDG UNG3 FDG Single-Strand Selective Monofunctional Uracil DNA Glycosylase EC 3.2.2.- EC 3.2.2
Location (GRCh38)
12:54121277-54189008
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001243787.2
Sequence length
2681.0 nt
GC content
0.5099

Transcripts

ID Sequence Length GC content
NM_001351242.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGAUGGGGUCUCAUUA… 2716 nt 0.5140
NM_001351243.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGCUGGAGUGCAAUG… 2683 nt 0.5166
NM_001351244.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGCUGGAGUGCAAUG… 3016 nt 0.5116
NM_001351245.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGCAGAUUAUGAGCUU… 2934 nt 0.5082
NM_001351246.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 3247 nt 0.5192
NM_001351247.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 2995 nt 0.5225
NM_001351248.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 2809 nt 0.5144
NM_001351249.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 3159 nt 0.5169
NM_001351250.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 2909 nt 0.5194
NM_001351251.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 2906 nt 0.5193
Showing 11 to 20 of 31 entries
Summary

This gene encodes a protein that participates in base excision repair by removing uracil from single- and double-stranded DNA. Many alternatively spliced transcript variants exist for this gene; the full-length nature is known for some but not all of the variants. [provided by RefSeq, Aug 2011]

Forensic Context

A topographic transcriptomic analysis in mice identified SMUG1 as one of five seed transcripts with highly specific enhanced expression in the nucleus accumbens shell (NAcSh) [Crofton et al. DOI:10.1016/J.Neuropharm.2020.108398].