Basic Information

Symbol
SMUG1
RNA class
mRNA
Alias
Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 HMUDG UNG3 FDG Single-Strand Selective Monofunctional Uracil DNA Glycosylase EC 3.2.2.- EC 3.2.2
Location (GRCh38)
12:54121277-54189008
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001243787.2
Sequence length
2681.0 nt
GC content
0.5099

Transcripts

ID Sequence Length GC content
NM_001351252.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 2806 nt 0.5143
NM_001351253.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 3120 nt 0.5147
NM_001351254.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 3121 nt 0.5146
NM_001351255.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 2765 nt 0.5150
NM_001351256.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 2891 nt 0.5178
NM_001351257.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGAGGAAGUAGGG… 3000 nt 0.5220
NM_001351258.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGCAGAUUAUGAGCUU… 2026 nt 0.5030
NM_001351260.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGCUGGAGUGCAAUG… 2570 nt 0.5136
NM_001351261.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGUGACAGCGGCAUG… 1177 nt 0.5234
NM_001351262.2 NCBI
AAAGGAACCGGAAACGGGAUGGGGAGCUGGACCAGGCUGGAGUGCAAUG… 2679 nt 0.5166
Showing 21 to 30 of 31 entries
Summary

This gene encodes a protein that participates in base excision repair by removing uracil from single- and double-stranded DNA. Many alternatively spliced transcript variants exist for this gene; the full-length nature is known for some but not all of the variants. [provided by RefSeq, Aug 2011]

Forensic Context

A topographic transcriptomic analysis in mice identified SMUG1 as one of five seed transcripts with highly specific enhanced expression in the nucleus accumbens shell (NAcSh) [Crofton et al. DOI:10.1016/J.Neuropharm.2020.108398].