Basic Information

Symbol
SNAI1
RNA class
mRNA
Alias
Snail Family Transcriptional Repressor 1 SNAH SLUGH2 SNAIL1 SNAIL SNA Snail Family Zinc Finger 1 Zinc Finger Protein SNAI1 Protein Snail Homolog 1 Protein Sna Snail 1 (Drosophila Homolog), Zinc Finger Protein Snail Homolog 1 (Drosophila) Snail 1 Zinc Finger Protein Snail 1 Homolog Snail Homolog 1 DJ710H13.1
Location (GRCh38)
20:49982980-49988886
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_005985.4
Sequence length
1705.0 nt
GC content
0.5842

Transcripts

ID Sequence Length GC content
NM_005985.4 NCBI
AUUGCGCCGCGGCACGGCCUAGCGAGUGGUUCUUCUGCGCUACUGCUGC… 1705 nt 0.5842
Summary

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008]

Forensic Context

A study in human menstrual blood-derived mesenchymal stem cells (MenSCs) from women with endometriosis demonstrated that the SNAI1 gene was overexpressed and involved in the upregulated epithelial-mesenchymal transition pathway [Penariol et al. DOI:10.3390/ijms231911515].