Basic Information

Symbol
SNAI2
RNA class
mRNA
Alias
Snail Family Transcriptional Repressor 2 SLUGH SLUGH1 SNAIL2 SLUG Snail Family Zinc Finger 2 Zinc Finger Protein SNAI2 Protein Snail Homolog 2 Slug Homolog, Zinc Finger Protein (Chicken) Slug (Chicken Homolog), Zinc Finger Protein Neural Crest Transcription Factor SLUG Neural Crest Transcription Factor Slug Snail Homolog 2 (Drosophila) Snail Homolog 2 WS2D
Location (GRCh38)
8:48917598-48921740
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003068.5
Sequence length
2180.0 nt
GC content
0.4124

Transcripts

ID Sequence Length GC content
NM_003068.5 NCBI
AGUUCGUAAAGGAGCCGGGUGACUUCAGAGGCGCCGGCCCGUCCGUCUG… 2180 nt 0.4124
Summary

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]

Forensic Context

No relevant information is available at the moment.