Basic Information

Symbol
SNAP91
RNA class
mRNA
Alias
Synaptosome Associated Protein 91 KIAA0656 AP180 CALM 91 KDa Synaptosomal-Associated Protein Clathrin Coat-Associated Protein AP180 Clathrin Coat Assembly Protein AP180 Phosphoprotein F1-20 Synaptosomal-Associated Protein, 91 KDa (Mouse) Homolog Synaptosomal-Associated Protein, 91kDa Homolog Synaptosome Associated Protein 91kDa Assembly Protein, 180kDa
Location (GRCh38)
6:83552880-83709691
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001242792.2
Sequence length
4422.0 nt
GC content
0.4629

Transcripts

ID Sequence Length GC content
NM_001376699.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4371 nt 0.4628
NM_001376700.1 NCBI
AGGGUGCGGAGAAGGGCAGCGGCCGAGUGACAGCUCCGCGGAGCGCUCC… 4222 nt 0.4493
NM_001376701.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4359 nt 0.4634
NM_001376702.1 NCBI
AGUGCGUGCCGGGUGCGGCGCCAGCAGCGGAGGGGCGGCCCGGCGCCCA… 4149 nt 0.4481
NM_001376703.1 NCBI
AGUGCGUGCCGGGUGCGGCGCCAGCAGCGGAGGGGCGGCCCGGCGCCCA… 4353 nt 0.4615
NM_001376704.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4139 nt 0.4465
NM_001376705.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4338 nt 0.4627
NM_001376706.1 NCBI
AGGGUGCGGAGAAGGGCAGCGGCCGAGUGACAGCUCCGCGGAGCGCUCC… 4189 nt 0.4490
NM_001376707.1 NCBI
AGGGUGCGGAGAAGGGCAGCGGCCGAGUGACAGCUCCGCGGAGCGCUCC… 4491 nt 0.4647
NM_001376708.1 NCBI
AGUGCGUGCCGGGUGCGGCGCCAGCAGCGGAGGGGCGGCCCGGCGCCCA… 4347 nt 0.4605
Showing 31 to 40 of 66 entries
Summary

Predicted to enable several functions, including clathrin adaptor activity; clathrin heavy chain binding activity; and phosphatidylinositol binding activity. Acts upstream of or within regulation of clathrin-dependent endocytosis. Predicted to be located in cytosol; postsynaptic density; and presynaptic membrane. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; cytoplasmic vesicle; and parallel fiber to Purkinje cell synapse. Predicted to be extrinsic component of presynaptic endocytic zone membrane. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2025]

Forensic Context

A study in mice demonstrated that the SNAP91 was identified as a hub gene related to synaptic plasticity during the addicting phase of nicotine self-administration in the ventral tegmental area [Fan et al. DOI:10.1016/J.Jgg.2024.08.009].