Basic Information

Symbol
SNAP91
RNA class
mRNA
Alias
Synaptosome Associated Protein 91 KIAA0656 AP180 CALM 91 KDa Synaptosomal-Associated Protein Clathrin Coat-Associated Protein AP180 Clathrin Coat Assembly Protein AP180 Phosphoprotein F1-20 Synaptosomal-Associated Protein, 91 KDa (Mouse) Homolog Synaptosomal-Associated Protein, 91kDa Homolog Synaptosome Associated Protein 91kDa Assembly Protein, 180kDa
Location (GRCh38)
6:83552880-83709691
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001242792.2
Sequence length
4422.0 nt
GC content
0.4629

Transcripts

ID Sequence Length GC content
NM_001376719.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4254 nt 0.4614
NM_001376720.1 NCBI
AGUGCGUGCCGGGUGCGGCGCCAGCAGCGGAGGGGCGGCCCGGCGCCCA… 4345 nt 0.4511
NM_001376721.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4512 nt 0.4612
NM_001376723.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4372 nt 0.4634
NM_001376726.1 NCBI
AGGGUGCGGAGAAGGGCAGCGGCCGAGUGACAGCUCCGCGGAGCGCUCC… 4223 nt 0.4499
NM_001376728.1 NCBI
GGCAGGAGCAGGGGAAGCAGAGUGACAAACAGUCUUAGAUUUGAUCCAG… 4037 nt 0.4384
NM_001376731.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4040 nt 0.4450
NM_001376733.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4034 nt 0.4440
NM_001376734.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4233 nt 0.4607
NM_001376735.1 NCBI
AGGGUGCGGAGAAGGGCAGCGGCCGAGUGACAGCUCCGCGGAGCGCUCC… 4374 nt 0.4529
Showing 51 to 60 of 66 entries
Summary

Predicted to enable several functions, including clathrin adaptor activity; clathrin heavy chain binding activity; and phosphatidylinositol binding activity. Acts upstream of or within regulation of clathrin-dependent endocytosis. Predicted to be located in cytosol; postsynaptic density; and presynaptic membrane. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; cytoplasmic vesicle; and parallel fiber to Purkinje cell synapse. Predicted to be extrinsic component of presynaptic endocytic zone membrane. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2025]

Forensic Context

A study in mice demonstrated that the SNAP91 was identified as a hub gene related to synaptic plasticity during the addicting phase of nicotine self-administration in the ventral tegmental area [Fan et al. DOI:10.1016/J.Jgg.2024.08.009].