Basic Information

Symbol
SNAP91
RNA class
mRNA
Alias
Synaptosome Associated Protein 91 KIAA0656 AP180 CALM 91 KDa Synaptosomal-Associated Protein Clathrin Coat-Associated Protein AP180 Clathrin Coat Assembly Protein AP180 Phosphoprotein F1-20 Synaptosomal-Associated Protein, 91 KDa (Mouse) Homolog Synaptosomal-Associated Protein, 91kDa Homolog Synaptosome Associated Protein 91kDa Assembly Protein, 180kDa
Location (GRCh38)
6:83552880-83709691
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001242792.2
Sequence length
4422.0 nt
GC content
0.4629

Transcripts

ID Sequence Length GC content
NM_001376736.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4013 nt 0.4451
NM_001376737.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 4130 nt 0.4610
NM_001376738.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 3711 nt 0.4441
NM_001376739.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 3470 nt 0.4239
NM_001376740.1 NCBI
GCAGCUCGGAGCGCUAGAGAGACGCGGCGGCGCUGGCAGAAGAGGCGGC… 3409 nt 0.4233
NM_014841.3 NCBI
AGUGCGUGCCGGGUGCGGCGCCAGCAGCGGAGGGGCGGCCCGGCGCCCA… 4437 nt 0.4618
Showing 61 to 66 of 66 entries
Summary

Predicted to enable several functions, including clathrin adaptor activity; clathrin heavy chain binding activity; and phosphatidylinositol binding activity. Acts upstream of or within regulation of clathrin-dependent endocytosis. Predicted to be located in cytosol; postsynaptic density; and presynaptic membrane. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; cytoplasmic vesicle; and parallel fiber to Purkinje cell synapse. Predicted to be extrinsic component of presynaptic endocytic zone membrane. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2025]

Forensic Context

A study in mice demonstrated that the SNAP91 was identified as a hub gene related to synaptic plasticity during the addicting phase of nicotine self-administration in the ventral tegmental area [Fan et al. DOI:10.1016/J.Jgg.2024.08.009].