Basic Information

Symbol
SNCB
RNA class
mRNA
Alias
Synuclein Beta Beta-Synuclein I(2)-Synuclein Β-Synuclein
Location (GRCh38)
5:176620082-176630672
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003085.5
Sequence length
1398.0 nt
GC content
0.6559

Transcripts

ID Sequence Length GC content
NM_001001502.3 NCBI
AGAGCUGCCGCAGCGCCGGAGCCGGAGCCGGAGCCGGAGCGCGCGAGCU… 1555 nt 0.6585
NM_001318034.2 NCBI
AGAGCUGCCGCAGCGCCGGAGCCGGAGCCGGAGCCGGAGCGCGCGAGCU… 1513 nt 0.6616
NM_001318035.2 NCBI
AGAGCUGCCGCAGCGCCGGAGCCGGAGCCGGAGCCGGAGCGCGCGAGCU… 1465 nt 0.6628
NM_001318036.2 NCBI
AGAGCUGCCGCAGCGCCGGAGCCGGAGCCGGAGCCGGAGCGCGCGAGCU… 1356 nt 0.6593
NM_001318037.2 NCBI
AGAGCUGCCGCAGCGCCGGAGCCGGAGCCGGAGCCGGAGCGCGCGAGCU… 1308 nt 0.6606
NM_001363140.2 NCBI
AGAGCUGCCGCAGCGCCGGAGCCGGAGCCGGAGCCGGAGCGCGCGAGCU… 1453 nt 0.6559
NM_003085.5 NCBI
AGAGCUGCCGCAGCGCCGGAGCCGGAGCCGGAGCCGGAGCGCGCGAGCU… 1398 nt 0.6559
Summary

This gene encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The encoded protein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Forensic Context

No relevant information is available at the moment.