Basic Information

Symbol
SNRNP70
RNA class
mRNA
Alias
Small Nuclear Ribonucleoprotein U1 Subunit 70 U1-70K RNPU1Z SNRP70 Snp1 RPU1 Small Nuclear Ribonucleoprotein, U1 70kDa Subunit Small Nuclear Ribonucleoprotein 70kDa (U1) U1 Small Nuclear Ribonucleoprotein 70 KDa U1 SnRNP 70 KDa Small Nuclear Ribonucleoprotein 70kDa (RNP Antigen) SnRNP70 U170K U1RNP U1AP1 U1AP
Location (GRCh38)
19:49085164-49108613
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003089.6
Sequence length
1671.0 nt
GC content
0.6338

Transcripts

ID Sequence Length GC content
NM_001301069.2 NCBI
AGUCGCUAUCGGAGGCCGCGCGGGUGGCUGAGCAGCGGCCUGGUGCGCU… 1644 nt 0.6308
NM_003089.6 NCBI
AGUCGCUAUCGGAGGCCGCGCGGGUGGCUGAGCAGCGGCCUGGUGCGCU… 1671 nt 0.6338
Summary

Enables U1 snRNA binding activity. Involved in mRNA splicing, via spliceosome and regulation of RNA splicing. Located in nucleoplasm. Part of U1 snRNP and spliceosomal complex. Implicated in disease of mental health and systemic lupus erythematosus. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that the SNRNP70 was identified as a housekeeping gene in the Information class and was differentially expressed between a specific male monozygotic twin pair, belonging to the least variable category of expression variation [Sharma et al. DOI:10.1152/physiolgenomics.00228.2003].